Clinical Benefits:

• P-Lift contains Vitex agnus-castus and vitamin B6 which assist in the management and relief of PMS symptoms such as breast tenderness, tiredness, moodiness, headaches, bloating and fluid retention.⁵ Vitamin B6 may help relieve emotional symptoms of PMS via its action as a cofactor for several neurotransmitters involved in mood regulation.⁶ Vitamin B6 has also been shown to manage fluid retention by assisting in the production of dopamine which has a dampening effect on aldosterone.⁷ Vitex relieves PMS symptoms by binding to dopamine receptors and inhibiting prolactin.¹ Elevated prolactin may inhibit corpus luteal development, reducing the secretion of progesterone in the luteal phase of the menstrual cycle.
• A clinical trial of 1634 PMS patients taking Vitex agnus-castus over three menstrual cycles showed 93% as reporting a significant decrease or total cessation of their PMS symptoms (Figure One).⁵ The symptoms that decreased include headaches, tiredness, moodiness, breast tenderness, bloating and fluid retention.⁵
• Vitex and ginger relieve menstrual pain.⁸ A double-blind comparative trial on 150 patients with dysmenorrhoea compared the effects of 1.0 g of ginger against two prescription medications. The study found this amount of ginger to be as effective as the prescription medicines at relieving menstrual pain.⁹ This is likely due to its anti-inflammatory and anti-prostaglandin actions.⁹