Melrose Nicotinamide Riboside Liposomal combines the latest in nutrient delivery technology, Plexozome™ together with bioavailable Nicotinamide Riboside to help support energy. Nicotinamide Riboside (NR) is a precursor for nicotinamide adenine dinucleotide (NAD+), a cofactor that is critical to cell metabolism. As we age, the demand on the NAD+ pool exceeds its availability, and NR helps to restore the depleted NAD+ levels.