BioClinic Naturals Opti EPA/DHA Plus SPM — High-Strength Fish Oil with Pro-Resolving Mediators

Opti EPA/DHA Plus SPM is a high-strength fish oil standardised to specialised pro-resolving mediators (SPMs), formulated to support the body's resolution of inflammation alongside cardiovascular, cognitive and visual health.

Per capsule: EPA 312mg · DHA 208mg · DPA 9.75mg · standardised SPMs 45.5mcg · Enteripure™ softgel · practitioner-grade.

What is Opti EPA/DHA Plus SPM?

This is a concentrated omega-3 fish oil that does something most fish oils do not: it is standardised to deliver SPMs — the molecules the body uses to actively resolve inflammation — in addition to the EPA and DHA from which they are made.

How omega-3s work — and the SPM breakthrough

EPA and DHA are long-chain omega-3 fatty acids incorporated into cell membranes, where they maintain membrane fluidity and serve as precursors to the signalling molecules that regulate inflammation, vascular tone and platelet activity. DHA is also a structural constituent of neural tissue and the retina. The newer and more interesting science concerns how inflammation ends: resolution is not a passive fading but an active, regulated process driven by a family of molecules — resolvins, protectins and maresins, collectively the SPMs — that the body synthesises from EPA and DHA. They signal the inflammatory response to switch off and the tissue to be cleared and repaired. This oil supplies those SPMs directly, not just their precursors.

Source and purity

Sourced from sustainably wild-caught, short-lived cold-water species (anchovy, sardine, mackerel, herring) that are naturally low in contaminants, and independently tested to GOED purity standards. The Enteripure™ softgel releases lower in the gastrointestinal tract, preventing reflux and fishy aftertaste.

Who it may suit

People with a high inflammatory load or focused on joint comfort; those supporting cardiovascular health and healthy blood lipids; anyone wanting brain, cognitive and eye support; and women wanting omega-3 (DHA) during pregnancy for foetal neural development.

How to take it

One capsule daily with food. Membrane incorporation is cumulative; benefits build over several weeks of consistent use.

Complementary nutrients

Commonly combined with CoQ10 and vitamin D for cardiovascular and immune support, and with curcumin for inflammatory conditions.

Indicated for

Support of the resolution of inflammation and joint health; cardiovascular health and healthy blood lipids; cognitive and visual function; and omega-3 (DHA) requirements in pregnancy.

Composition

Per capsule: EPA 312mg, DHA 208mg, DPA 9.75mg and standardised total pro-resolving mediators 45.5mcg, in an Enteripure™ softgel. 60 capsules. Also available in 120 capsules.

Practitioner-grade. Always read the label and follow the directions for use. If symptoms persist, consult your healthcare professional.